FESSH prep Compressive neuropathies Pathophysiology — compression and traction
Pathophysiology of peripheral nerve compression and traction injury
Pathophysiology of peripheral nerve compression and traction injury.
1.Peripheral nerve compression is a combination of mechanical compression and ischaemic injury, leading to nerve dysfunction.
2.Posterior interosseous nerve syndrome at the radial tunnel typically presents with finger and thumb extension weakness without sensory loss because the superficial branch of the radial nerve has already separated proximally.
3.With continued compression, intraneural fibrosis can develop, further limiting recovery potential.
4.Nerve conduction studies in early radial nerve compression always show conduction block.
5.In experimental models, modest stretch of a peripheral nerve impairs intraneural blood flow and conduction, with measurable amplitude reduction occurring at strains as low as 6%.
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